FWIW, many online shooter games work just fine. Those with extremely invasive kernel-level anticheat do not. Some of those with less-invasive anticheat also do not.

So, yeah, shit like the latest CoD, Valorant, Apex Legends [0], and that godawful Marathon game won't run... but that's because of active work by the devs to make it so that it won't.

[0] ...for some crazy reason...